Because of this fact the hydration behavior of crystalline APIs is of particularly high importance within the pharmaceutical industry, and is vastly studied from every possible angle. The state of hydration has a direct effect on the physical properties of the API, which in turn has a large impact on the drug processability and how the drug will eventually perform in-vivo, i.e. stability, solubility, and bioavailability.http://www.nmn-bio.com/biological-api/
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